Henry married Lady Mary Gertrude Weddell on 5 July 1832. Mary (daughter of Thomas Philip (de Grey), 2nd Earl de Grey of Wrest and Lady Henrietta Frances Cole) died on 11 July 1892 in Newby Hall, Skelton, Yorkshire, England. [Group Sheet] [Family Chart]

1. Henry Frederick Clare Vyner was born in 1836; died on 11 Nov. 1882 in Cockley Cley, Norfolk, England.
2. Reginald Arthur Vyner was born in 1839; died on 28 Sept. 1870.
3. Captain Robert Charles de Grey Vyner was born on 13 Feb. 1842; died on 19 March 1915 in 45, Egerton Crescent, Kensington, Middlesex, England.
4. Frederick Grantham Vyner was born in 1847; died on 21 April 1870 in Dilesi, Bœotia, Greece.
5. Henrietta Anne Theodosia Vyner died on 28 Feb. 1907.
6. Theodosia Vyner died on 18 Nov. 1864.